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Sonodynamic Therapy
Sonodynamic therapy is the use of ultrasound to enhance the cytotoxic action of naturally occurring chloropyll derivatives, referred to as porphyrins.  The therapeutic process is non-invasive and produces no negative side effects.   "Sonodynamic therapy appears to be a promising modality for cancer treatment since ultrasound can penetrate deep within the tissue and can be focused on a small region of tumor to chemically activate relatively non-toxic molecules. (e.g.  porphyrins ) thus minimizing undesirable side effects"  (Annals of the New York Academy of Sciences--899:335-348 (2000).  For more information, read below.

 

 



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1.800.359.6547

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1.702.581.9120

After hours hot line:
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What is it?
In a nutshell, Sonodynamic therapy is the use of low level ultrasound, along with naturally derived sensitizers, to produce tumor destruction, especially cavitations in malignant cells.


Is it effective?
The use of ultrasound allows deeper penetration for treatment of such tumors as those which may be located in the lungs and liver. Case studies, however, show equally effective results for breast cancer, prostate cancer, ovarian cancer, and skin originated cancers, such as melanoma and squamous cell carcinoma.


How long has this been used?
Therapies employing Sonodynamics have been around since the late 1800's, but their efficacy was limited by the marginal effect that available sensitizers (primarily chemotherapeutic agents) had on cancer cells.  Even without effective sensitizers, the treatment showed merit in treating, particularly, shallow tumors. 


What is new regarding this treatment?
In the late 1990's new, non-toxic agents were developed in Russia using, primarily, derivatives of Chlorphyll and algae. These sensitizers were far more effective, and in the intervening years, testing and treatment have shown great promise.

 

 

How is it administered?
The sublingual sensitizer is administered and the porphyrin molecules travel through the blood stream and accumulate in the cancer cells. The sensitizer is administered twice daily for four days. On the fifth day, no sensitizer is administered, and on the sixth day, the ultrasound therapy begins. Ultrasound is applied to the primary cancer site for approximately 30 minutes, then an additional 30 minutes of ultrasound is applied to the torso and/or extremities (as appropriate) to destroy any metastasis. The potential to eradicate the metastatic process is a truly exciting aspect of this treatment, since metastasis is not identifiable until the cancer actually attaches itself to a secondary site. In conjunction with the Sonodynamic Therapy, patients will receive other therapies by the clinic. 
What are the side effects?
Ordinarily, the only side effects experienced will be a feeling of tiredness as the healing and detoxification processes take place. Ultrasound scans will be done at the beginning of treatment and will be done again at the end of the treatment.  Some patients will have a dramatic and visual change in their tumor mass in a short period of time, while others may not see any immediate change.  Patients will be provided CD's showing the initial ultrasound results and the final ultrasound results.